The harness is called a security gateway bypass. There is a security gateway in between the OBD port and the canbus system, and also secures the radio from the canbus system separate from the OBD port so the vehicle can’t be hacked and controlled via the radio. The gateway will allow information to be presented to a scan tool from the bus, but not the other way around- so it needs to be bypassed for any changes to be made, or any fault codes to be cleared. It can be removed when done using it, and is not needed at all to just connect to modules and read them, only when an actual change is to be made. Example- everything trek97 has done above so far, the 12+8 bypass was not needed.
AlfaOBD does not marry to the vehicle, it is just a bi-directional scan tool. It can be used on any ~2006+ FCA vehicle.