Perhaps, but it would need to get a lower fuel economy to reduce the amount the manufacture is paying in fines for failing CAFE standards. I say my Dakota got the same MPG as the Ram, but in reality it might have gotten 1 or 2 mpg better. It just wasn't enough of a difference to sway me to keep going with a vehicle with not nearly the capability.
I'm pretty sure it doesn't matter how big the pickup is. It will still fit into the exact same "Light Duty Truck" CAFE category as the 1500. The important thing will be sales volume and mpg.
In 2025 manufactures of light duty trucks are supposed to average 39.3 MPG for light duty trucks and 55.3 MPG for passenger cars. I don't believe manufactures have met the average standard for many years as a result must pay fines for every vehicle that fails the standard. If they meet the average fleet standards I don't believe they pay any fines even if a few vehicles fail to meet the standard. From what I read the fine is $14 for every 0.1 mpg below the standard. So, if Ram does does not meet the average light truck standard in 2025, which they won't, and they sell you a truck that averages 20MPG they will have paid a $2700 CAFE fine on that single truck and passed that cost along to you.
Ram sales around 500,000 trucks annually so if they can get just 1 mpg better in 2025 that will reduce their CAFE fines by around 70 million dollars. That's a huge savings for them. Perhaps one of the reasons they are abandoning the hemi for the hurricane. If they can convince you to not buy a Ram in favor of a smaller pickup that might get 2 or 3 mpg better that's and even bigger savings especially if they sell it at the same profit margin. I think the average CAFE standards are so far out of reach for the manufactures at this time that they are resigned to just reducing the fines they pay.