Personally, there is NO WAY I would ever invest in/buy another 3.6 V6 in full size truck, period.
(A V6 in a compact pickup is well suited for it, like the 3.8 V6 in the third gen Frontier)
I've had a 3.6 Pentastar in a number of FCA vehicles, including the Dodge Charger, and the Jeep Grand Cherokee (the size and weight of the JGC was almost too much for the V6) , and a RAM over the years.
That V6 belongs in a car or an SUV, NOT in a truck, IMO.
Before I traded for the '23, I even test drove a Quad Cab V6, the constant 5-6-7-8 shifting drove me crazy (as it did when I had one before). Going up even a small incline in the road caused it do downshift 2-3 gears. Honestly, I can't imagine towing in a V6 (maybe if you're on a level pavement your entire trip.)
My test drive lasted about 5 minutes, I drove it back to the dealer, and parked it in the same place it was when I arrived along with all the other V6's the dealer had)
I jumped in the '23 Hemi, and it was a difference between night and day. I had one downshift from 8th to 7th going up a small hill. And mind ya, this was a 3.21 axle ratio. (Of course, I already had a HEMI).
I could have walked away with a significant $$$$$$ If I had went for the V6, but I would have regretted it.
I do no hauling, and no towing, but I still would have hated the constant gear hunting because of the lack of power in the V6.
Again, my personal opinion and experience.