My truck is brand spanking new and so far my best reading is 15 MPG !!!!
My first few tanks was low as well, 12-15 average. But that was during break-in where I did a lot of heavy acceleration runs on the the highway ramps to ensure a good break-in process per the owner's manual. Plus there was a lot of idling time playing with the myriad of settings in the 12" display.
It's been pretty hot out so the air has been running but dam, we are way off the estimated MPG
Running the A/C doesn't really make any difference on today's vehicles. Keeping the windows closed helps with aerodynamics and improves mileage. Feel free to use the A/C and use cruise control on the highway.
EPA estimates are approximations of driving conditions. For my 2022 RAM 1500 4WD 5.7L estimated mileage is 15/17/21 according to the EPA (city/combined/hwy). Fuel mileage on the dash display is an average which includes idling in your driveway at 0 mpg, sitting at the grocery store at 0 mpg, etc. which the EPA does not factor in, they simply provide estimated mileage while driving in stop/go traffic, or free flowing highway.
If you want to know what you're actually getting while driving in the city and on the highway, you have a couple options. Use the "Current MPG" readout which shows live fuel consumption rate, or reset your A or B trip when you leave for a drive to work or on a highway trip. Pure highway cruise I've managed a best of 23.6 mpg on a 40 mile trip at 68 mph. Typical is 21-22. Pure city driving I've managed 18, but every city is different and where you drive greatly affects how much stop and go traffic you experience. My truck has 3.92 gears (I keep it under 2k rpm) so if you have 3.21 you can expect slightly better on the highway and at higher speeds, but driving style greatly affects it.
I'm beating the EPA mileage ratings and exceeding my expectations of the truck, so I'm happy.