I had the whistle-type noise at high speeds and especially into headwinds. I ultimately figured out that it was the seal between the door and the truck down the A-Frame next to the windshield. I bought a cheap roll of automotive rubber weatherstripping from Home Depot and ran it down both doors behind the existing rubber door seals and it resolved it completely (except for extreme headwind conditions).
My conclusion was that the mirrors catch so much air, that it pulls the on the front of the door seal (between the fender and the roof) just enough to let air slip by and create the annoying sound.
Give it a try…it could save your sanity.