Most likely a hardware issue.
Any signs of a water-leak in the back?
"Passive entry.
Immobilizer System - RF-Hub uses a high security encryption system called Advanced Encryption Standard (AES) for the Immobilizer System. The RF-Hub marries itself to the BCM and Powertrain Control Module (PCM) with AES at first ignition ON in the assembly plant. Then the system marries the key fobs, RF-Hub, BCM and the PCM with unique secret keys for each vehicle. Swapping any of the married parts ARE NOT ALLOWED in the new system.
Passive Entry (PE) - The RF-Hub also uses AES for PE operation. If the Smart door handles or exterior release switches are activated, the RF-Hub signals the LF antennas. The LF antenna wakes up the key fob then sends a challenge to confirm if it is the correct key fob. Then the key fob responds back to the RF-Hub via the internal RKE antenna or the Remote Start Antenna (RSA) with the challenge response. When a valid key fob is recognized by the RF-Hub, a CAN data bus message is sent to the BCM to lock or unlock the vehicle by the RF-Hub"
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