3.92, 5.7 etorque with the 33 gallon tank: I get about 16.5 driving around town. I drive with a light foot and drive like the 50 year old I am! On the highway, it really depends on average speed. If it is a slower local highway, it will see 21-22mpg at 50-60mph. If the average speeds are higher, say 70-75mph, it will drop to 19.5mpg or so. Loaded with a trailer (5-6k pounds), depends entirely on terrain but will see high single digits to low teens. I always use tow/haul so the transmission will stay in a lower gear but the truck hauls beautifully.
Personally, I would not spec the half ton Ram without the higher numerical differential because otherwise, for me at least, it undermines the utility of owning a full size truck. If I wanted to get by with 5-6k pounds useful towing capacity, I would also check out a smaller truck like a Tacoma or a Ridgeline. But if you are not towing, and just need the bed offered by a full size truck, the lower numerical differential will give you a nice bump in fuel economy. Different tools for different jobs, but they all work well.
Personally, I would not spec the half ton Ram without the higher numerical differential because otherwise, for me at least, it undermines the utility of owning a full size truck. If I wanted to get by with 5-6k pounds useful towing capacity, I would also check out a smaller truck like a Tacoma or a Ridgeline. But if you are not towing, and just need the bed offered by a full size truck, the lower numerical differential will give you a nice bump in fuel economy. Different tools for different jobs, but they all work well.