Okay so based upon what you said they will not work in drive. My truck is not a Cali or Mississippi truck.
When in drive and I hit the button for the cargo lights I don't get the indicator in the cluster. It only comes on once I put it into R, N, P so I think something is still off.
However, I'm also having some other odd, but minor issues. Some of the buttons don't light up at night when the headlights are turned on (front/rear defroster, recirculate, Auto, and mode), but they do function. When activated the orange "ON" indicator turns on, but its super dim. When the lights are turned off, the orange indicator functions completely normal and isn't super dim. Also, the adjustor to adjust the dash brightness works completely normal when the headlights are turned on manually, but sometimes when its on auto the brightness is maxed out and the adjustor does nothing. Then all of a sudden it randomly starts working (I have noticed it seems it doesn't work when its just starting to get dark out, but once it gets fully dark it seems to start working).