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5th gen Ram 1500 P0300 code saga - would love some ideas

Bayou72

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2019 Ram 1500 (not classic) Limited (Hemi 5.7 with etorque) 126k miles - only aftermarket is Corsa exhaust (installed before 5k miles)

I will try and make this as short as I can but give the full depth of what has occurred, thanks for your patience!

Problem started with getting a random evap leak code (sometimes small, sometimes large P0456 & 7). I have a OBDLink MX+, so I read codes from CEL and saw P0456 first. Would occur within 30 seconds of startup. I reset first time and it would not reproduce consistently but may go days to a couple weeks between occurrences. I checked hoses around evap system for deterioration (none found, but no smoke machine checks). This happens over couple months and would never repeat but stayed randomly over long time intervals. I had to go out of town and left truck at airport parking for around 4 days. Returned and was headed home, about 2 miles from parking garage when I noticed an abnormal feeling to truck like a miss, and within 30 seconds it worsened and CEL came on and truck acted like it was in a limp mode where it wouldn't want to accelerate (still missing). I pulled into next available safe spot and turned off, then turned ignition on and ran codes and got the following back.
Codes
U11B9-00 Lost communication with RF Hub
B169B-2A Cargo Lamp Switch Stuck
U1516-87 RF Hub Secret Code - Missing Message
U0645 Lost communication with Active Air Dam module
P0171 Fuel System 1/1 Lean
P0300 Multiple cylinder misfire
U11B900-00 same as #1 above (I don't know why this one listed twice but it did under confirmed, see pic attached)

I cleared codes and tried restart and it repeated like 3-4 times so I shut it down never letting it run more than 10 seconds. Cleared codes again, then disconnected negative battery terminal and waited 30 minutes. Cranked up, ran like normal. I monitored all gauges thru cluster to look for abnormalities. Did the same with OBDLink to see if anything was out of the ordinary, all green. Proceeded to drive and see what happened. Drove normal, no issues for ~45 miles to house. At home, I checked RF Hub location and back glass area for leaks, dry as a bone and no water residue or evidence that it had been leaking.

Truck was driven every day for short distances with no issues, then on like 4th or 5th day after previous occurrence was headed out when it started again, approximately 2 miles from home so turned around and limped back. Did same process as before and had same result, it went back to normal. I made a 1000 mile trip during this time with no problems, truck ran like it had for 125k miles.

After perhaps a month I started getting the P0456 & P0457 codes again randomly, then one day the P0300 comes back. During resets and playing with it once or twice it threw P0307 (twice perhaps) but mainly its the P0300 code. Truck will not stay running now. When cranked it starts and idles up to ~1500 rpm then begins to sputter and will die within 10 seconds.

I am aware of the lifter/cam issues but the random misfire makes me doubtful. When researching I see that it could be faulty spark plugs or coils (plugs changed around 100k with NGK Iridium IX plugs), 02 sensors, fuel injectors, burned exhaust valve, catalytic converter, camshaft position sensor (i removed and replaced both this and crank sensor with OEM Mopar parts as they are cheap), defective ECM.

My last step was the replacement of cam & crank position sensors to no avail. Wanted to reach out and see if I can get some input from anyone who may have seen this or has a friend who has had this problem.

I am really wondering about the ECM because how random it is happening. I did check grounds and noticed ECM was slightly loose so tightened the 10mm bolts but problem persists.

I would love some input of laundry list to check and perhaps most logical order as ECM is not a cheap part...

Thanks to all who read and provide feedback.
 

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Great question, my bad for not mentioning it above. I did also check it, probably in the middle of this saga about 3 weeks ago and found it to be holding low around 12.3V so I took it to where I had purchased as 3 year warranty was running out in November and it failed so they replaced. So new battery and hasn't affected anything but I know that this is case sometimes. Thanks
 

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