Michelin LTX M/S are hard to beat for every day, non serious offroad use. I had them on my previous F150, currently on my wife's Grand Cherokee, and on several vehicles through out the family over the years. Smooth, quiet, and outstanding all weather performance.
My factory 22" Goodyears are nearly done at just 19K, so i'm currently shopping. I was dead set on Michelin's until I saw the price ($1,800 w/ certificates at Discount) and started browsing around a little more. The Continental Terrain Contact H/T have my attention at the moment. Same 70K warranty as the Michelin's, high ratings, similar tread pattern, and about $300 cheaper installed. I haven't decided if it's worth the try yet.